Li Lab

The British journal of dermatology · 2013

Propranolol induces apoptosis of human umbilical vein endothelial cells through downregulation of CD147

Xie, W. and Xie, H. and Liu, F. and Li, W. and Dan, J. and Mei, Y. and Dan, L. and Xiao, X. and Li, J. and Chen, X.

doi:10.1111/bjd.12193


Abstract

Infantile haemangiomas (IHs) are benign tumours in infancy. Most patients suffering from IHs do not require treatment. However, if there is a dramatic aesthetic or functional impairment, treatment is needed. Currently the most promising therapy for complicated IHs is the oral administration of propranolol, but its mechanism is unclear.

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