Li Lab

JAMA dermatology · 2026

Systemic Proteomic Alterations and Predictive Biomarkers of Paroxetine Response in Refractory Rosacea: A Secondary Analysis of a Randomized Clinical Trial

Wang, B. and Deng, X. and Zhang, Y. and Xiao, X. and Jian, D. and Shi, W. and Liu, F. and Zhao, Z. and Tang, Y. and Chen, M. and Deng, Z. and Li, J. and Huang, Y. and Huang, J. and Zhang, Y.

doi:10.1001/jamadermatol.2026.1437


Abstract

Rosacea is a chronic inflammatory cutaneous disorder characterized by persistent erythema and vascular dysregulation. While paroxetine has shown clinical efficacy in reducing these symptoms, the systemic molecular mechanisms underlying its therapeutic response remain poorly characterized.

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