Li Lab

Annals of medicine · 2026

Tranexamic acid protects human dermal fibroblasts from D-galactose-induced senescence via the GPR30/MAPK pathway

Lin, Y. and Wang, Y. and Wang, W. and Deng, Z. and Zhang, Y. and Peng, Y. and Tang, J. and Li, J. and Huang, C. and Jian, D.

doi:10.1080/07853890.2026.2663263


Abstract

Tranexamic acid (TXA) is widely used for pigmentary disorders, but its anti-ageing potential remains unclear. This study aimed to evaluate whether topical 3% TXA improves early periorbital wrinkles in women with facial melasma and to investigate whether TXA protects human dermal fibroblasts from D-galactose-induced senescence

← Back to publications