Li Lab

Journal of dermatological science · 2010

Depletion of CD147 sensitizes human malignant melanoma cells to hydrogen peroxide-induced oxidative stress

Li, J. and Peng, L. and Wu, L. and Kuang, Y. and Su, J. and Yi, M. and Hu, X. and Li, D. and Xie, H. and Kanekura, T. and Chen, X.

doi:10.1016/j.jdermsci.2010.03.022


Abstract

Increased sensitivity to reactive oxygen species (ROS) contributes to the effectiveness of therapeutic strategies in patients with malignant melanoma (MM). CD147, a cell surface receptor for cyclophilin A (CypA), is thought to exert antioxidant activities.

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