Jian, D. and Jiang, D. and Su, J. and Chen, W. and Hu, X. and Kuang, Y. and Xie, H. and Li, J. and Chen, X.
doi:10.1016/j.steroids.2011.06.008
Abstract
It is well known that melanin synthesis in melanoma cells is controlled by melanogenic enzymes, which regulate the cAMP-PKA signaling pathway. Estrogen was previously reported to upregulate melanogenesis that is associated with human skin pigmentation.