Li Lab

Computational and structural biotechnology journal · 2024

PANoptosis signaling enables broad immune response in psoriasis: From pathogenesis to new therapeutic strategies

XM. Hu, S. Zheng, Q. Zhang, X. Wan, J. Li, R. Mao, R. Yang, and K. Xiong

doi:10.1016/j.csbj.2023.11.049


Abstract

Accumulating evidence suggests that regulated cell death, such as pyroptosis, apoptosis, and necroptosis, is deeply involved in the pathogenesis of psoriasis. As a newly recognized form of systematic cell death, PANoptosis is involved in a variety of inflammatory disorders through amplifying inflammatory and immune cascades, but its role in psoriasis remains elusive.

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