Li Lab

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2019

Thalidomide ameliorates rosacea-like skin inflammation and suppresses NF-κB activation in keratinocytes

Chen, M. and Xie, H. and Chen, Z. and Xu, S. and Wang, B. and Peng, Q. and Sha, K. and Xiao, W. and Liu, T. and Zhang, Y. and Li, J. and Deng, Z.

doi:10.1016/j.biopha.2019.109011


Abstract

Rosacea is a chronic inflammatory skin disorder of uncertain etiology. Evidence suggests the underlying pathogenesis is modulated by abnormal inflammatory and vascular responses. Thalidomide is a synthetic derivative acid with anti-inflammatory and anti-angiogenic properties. However, its effects on rosacea remain unknown.

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